THE CORRELATION BETWEEN LDL/HDL RATIO AND ACUTE CORONARY SYNDROME AMONG PATIENTS AT RSUD ABDUL WAHAB SJAHRANIE SAMARINDA

Monika Widi Sherina; Siti Khotimah; Muhammad Furqon

Monika Widi Sherina Universitas Mulawarman
Siti Laboratorium Ilmu Biokimia, Fakultas Kedokteran, Universitas Mulawarman
Muhammad Laboratorium Ilmu Penyakit Dalam, Fakultas Kedokteran, Universitas Mulawarman

Keywords: Acute coronary syndrome;, LDL ratio;, HDL ratio;

Abstract

Acute coronary syndrome is part of clinical manifestation of coronary heart disease. It is a collection of clinical symptoms caused by the presence of atherosclerotic plaques. LDL is oxidized lipoprotein produced in the body which is captured by macrophage. It may be accumulated in blood vessels and can cause atherosclerotic plaques. HDL transports cholesterol from blood vessels and carries it back to the liver to directly flush it in order to prevent atherosclerotic process. High LDL level and low HDL level accompanied by their ratio increase are associated with an increased risk of heart disease. This study aims to find the correlation between LDL/HDL ratio and acute coronary syndrome among patients admitted to ICCU at RSUD Abdul Wahab Sjahranie Samarinda. The design of this study was analytical observational with cross-sectional method. Using purposive sampling technique, the medical records of patients admitted to ICCU at RSUD Abdul Wahab Sjahranie Samarinda in 2019 were used as the data. The data were analyzed using Chi-square test. Out of 56 samples, 27 patients (48.2%) had low LDL/HDL ratio and 29 patients (51.8%) had high LDL/HDL ratio. Based on the Chi-square test, it was found that p value was 0,035 (p < 0,05). It can be concluded that there is correlation between LDL/HDL ratio and acute coronary syndrome.

Keywords: Acute coronary syndrome, LDL/HDL ratio

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