KARAKTERISTIK PASIEN LIMFOMA YANG DILAKUKAN PEMERIKSAAN IMUNOHISTOKIMIA CD20 DI LABORATORIUM PATOLOGI ANATOMI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA PERIODE 2017–2020

Mutmainnah Mutmainnah; Hadi  Irawiraman; Moriko Pratiningrum

Mutmainnah Mutmainnah Program Studi Kedokteran, Fakultas Kedokteran Universitas Mulawarman Samarinda
Hadi Irawiraman Laboratorium Patologi Anatomi Fakultas Kedokteran Universitas Mulawarman, Samarinda
Moriko Pratiningrum Laboratorium Telinga Hidung Tenggorokan – Kepala Leher, Fakultas Kedokteran Universitas Mulawarman, Samarinda

Keywords: Lymphoma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Immunohistochemistry CD20 Treatment

Abstract

Lymphoma is a malignant, deadly cancer and many people from developed and developing countries may be still diagnosed with it. The location and subtype of lymphoma cancer will determine the management and prognosis among lymphoma patients. Due to the different management and prognosis of lymphoma, immunohistochemistry CD20 (Cluster of Differentiation 20) is required to help diagnose Non-Hodgkin lymphoma or Hodgkin lymphoma. This study is aimed at finding the characteristics of lymphoma patients treated with immunohistochemistry CD20 at the Anatomic Pathology Laboratory Abdul Wahab Sjahranie Regional Public Hospital, Samarinda from 2017 to 2020. This was a descriptive study applying cross sectional approach. The data were patient’s medical records obtained at Abdul Wahab Sjahranie Regional Public Hospital, Samarinda. There were 205 patients fulfilling the inclusion criteria. The results of the study on lymphoma patients who treated with CD20 immunohistochemical examination showed that the incidence of lymphoma in 2017 was 30.7% (n=63), in 2018 it was 33.2% (n=68), in 2019 it was 20% (n=41) and in 2020, namely 16.1% (n=33), lymphoma patients who treated with immunohistochemical examination of CD20 were 61.2% (n=205) and without CD20 were 38.8% (n=130), lymphoma in men was 62, 4% (n=128) and women 37.6% (n=77), the highest age group was 46-65 years as much as 45.4% (n=93), the most lymphoma locations were lymphoma nodal colli, it was 40.5% (n=83) and abdominal extranodal lymphoma was 22.9% (n=47), the results of immunohistochemical CD20+ were 86.8% (n=178) and CD20- was 13.2% (n=27), the type of lymphoma in Non-Hodgkin's lymphoma was 91.2% (n=187) with the most subtype DLBCL 72.2% (n=148) and Hodgkin's lymphoma was 8.8% (n=18) with the most subtype Nodular Sclerosis 5.9% (n=12). Based on this study, it can be concluded that the incidence of lymphoma who treated with CD20 immunohistochemical examination for the period 2017-2020 was 205 patients, the highest number of lymphoma patients was in men, age group 46-65 years, lymphoma nodal colli, type of Non-Hodgkin's Lymphoma with subtype DLBCL.

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