HUBUNGAN STRES DENGAN KADAR HBA1C PADA PASIEN RAWAT JALAN DIABETES MELLITUS TIPE 2
Abstract
HbA1c level is glycosylated hemoglobin which reflects the average blood glucose level for the last three months. In T2DM patients, regular HbA1c levels are checked as an evaluation of the management of glycemic control. One of the factors that can affect the increase in blood glucose levels is stress. Stress increases levels of the hormone cortisol which promotes the breakdown of glucose stored in the body. This study aims to determine the relationship between stress levels with HbA1c levels in T2DM patients at the Outpatient Installation of RSUD Abdoel Wahab Sjahranie. The research is an analytic observational with a cross-sectional design. Data were collected using a purposive sampling technique by filling in Perceived Stress Scale instrument by the patient and recording the results of HbA1c levels. Samples that met the inclusion criteria were 68 samples. Statistical analysis using chi-square test, p value <0.05 with 95% confidence interval was considered significant. The results showed that in patients who experienced mild stress, the majority (67.6%) had controlled HbA1c levels. For patients with moderate and severe stress, the majority had uncontrolled HbA1c levels (47.1% and 20.6%, respectively). The statistical test showed a p-value = 0.014 which means there is a relationship between stress and HbA1c levels in T2DM patients.
References
Arania, R. et al. (2021) “Hubungan antara Usia, Jenis Kelamin dan Tingkat Pendidikan dengan Kejadian Diabetes Mellitus di Klinik Mardi Waluyo Lampung Tengah,” Jurnal Medika Malahayati, 5(September), hal. 146–153. doi: 10.1007/s00712-023-00827-w.
Badedi, M. et al. (2016) “Factors Associated with Long-Term Control of Type 2 Diabetes Mellitus,” Journal of Diabetes Research. Diedit oleh U. Rothe. Hindawi Publishing Corporation, 2016, hal. 2109542. doi: 10.1155/2016/2109542.
Boku, A. (2019) Faktor-Faktor yang Berhubungan terhadap Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe II di RS PKU Muhammadiyah Yogyakarta, Skripsi.
Davies, M. J. et al. (2022) “Management of Hyperglycemia in Type 2 Diabetes,” Diabetes Care, 45(11), hal. 2753–2786. doi: 10.2337/dci22-0034.
Fitria, N. et al. (2022) “Analisis Efektivitas Biaya Penggunaan Metformin-GlimepirideTerhadap Penurunan Kadar Gula Darah Puasa Pada Pasien Diabetes Mellitus Tipe 2 di RS Universitas Andalas,” Jurnal Sains Farmasi & Klinis, 9(Desember), hal. 202–207. doi: 10.25077/jsfk.9.sup.202-207.2022.
Hary, Z. A. P. (2017) Hubungan antara Kelekatan Terhadap Ibu dengan Tingkat Stres pada Mahasiswa Perantau. Universitas Sanata Dharma.
International Diabetes Federation (2021) IDF Diabetes Atlas. 10th ed, Diabetes Research and Clinical Practice. 10th ed.
Jannah, R. (2019) Analisis Faktor yang Berhubungan dengan Stres pada Pasien Diabetes Mellitus di Puskesmas Surabaya. Universitas Airlangga.
Kementerian Kesehatan Republik Indonesia (2020) “Tetap Produktif, Cegah Dan Atasi Diabetes Mellitus,” Pusat Data dan Informasi Kementrian Kesehatan RI.
Perkumpulan Endokrinologi Indonesia (2021) Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia 2021. PB PERKENI. Tersedia pada: https://pbperkeni.or.id
Putri, E. M. et al. (2018) Hubungan Lingkar Pinggang dan LILA dengan HbA1c Pada Obesitas. Universitas Diponegoro.
Rita, N. (2018) “Hubungan Jenis Kelamin, Olah Raga Dan Obesitas Dengan Kejadian Diabetes Mellitus Pada Lansia,” Jurnal Ilmu Kesehatan, 2(1), hal. 93–100. doi: 10.33757/jik.v2i1.52.
Saputra, M. D. dan Muflihatin, S. K. (2020) “Hubungan Stres dengan Terkendalinya Kadar Gula Darah pada Pasien DM Tipe II di Irna RSUD Abdul Wahab Sjahranie Samarinda,” Borneo Student Research, 1(3), hal. 1672–1678.
Sarihati, I. G. A. D., Karimah, H. N. dan Habibah, N. (2018) “Gambaran Kadar HbA1c pada Pasien Diabetes Melitus Tipe 2 di RSUD Wangaya,” The Journal of Medical Laboratory, 6(2).
Sharma, K. et al. (2022) “Stress-Induced Diabetes: A Review.,” Cureus. United States, 14(9), hal. e29142. doi: 10.7759/cureus.29142.
Wardani, D. A. K., Sugiarto, S. dan Cilmiaty, R. (2018) “Stress, Nutritional Status and Blood Glucose Levels among Patients with Diabetes Mellitus Type 2,” International Journal of Public Health Science (IJPHS), 7(4), hal. 283–288. doi: 10.11591/ijphs.v7i4.14914.
Wong, H. et al. (2019) “The Effects of Mental Stress on Non-insulin-dependent Diabetes: Determining the Relationship Between Catecholamine and Adrenergic Signals from Stress, Anxiety, and Depression on the Physiological Changes in the Pancreatic Hormone Secretion.,” Cureus. United States, 11(8), hal. e5474. doi: 10.7759/cureus.5474.
World Health Organization (2016) “Global Report on Diabetes.” Tersedia pada: https://apps.who.int/iris/handle/10665/204871.